Chemistry Department

Senior Thesis Titles

Recent senior theses are listed here by title, student name, faculty advisor. A complete listing of thesis titles is available via the on-line catalog of the Reed College library.

2016

Chemistry

Pulsed Nd: YAG laser Raman spectroscopy and normal coordinate analysis of trivalent bismuth complexes, Joohee Bang (Gerrity)

Elucidating the water reducing mechanism of bis-2-mercaptopyridine-N-oxide nickel(II) as a model for the design of next generation water reducing catalysts, Carlo Berti (Kliegman)

Spinosad analysis of apples in the Pacific Northwest, Nich Hanson (Cass)

Couches on fire!: polybrominated diphenyl ethers and your dorm room, Jesyca Hernstadt (Kliegman)

Coal trains and the world: modeling the dispersion of fine particulate matter in the Columbia River Gorge, Katherine Jentoft-Herr (Walsh)

Tropospheric particle formation in forests: global modeling of secondary organic aerosol production from reaction of NO3 radical with speciated monoterpenes, Makoto Kelp (Fry)

Separation and quantification of radioactive 14C from irradiated graphite, Ilana Novakoski (Walsh)

Probing the activity of bismuth phosphates for asymmetric catalysis, Nick Till (LaLonde)

Preparing and characterizing bis(imino)pyridine complexes of nickel, iron and cobalt for electrocatalytic hydrogen evolution, Sam Underwood (Kliegman)

Proteins, DNA, electrons, and a little bit of uranium : protein·DNA complexes and cryo-electron microscopy, Jazz Weisman (Glasfeld)

Quantitative analysis of liquid matrices using laser-induced breakdown spectroscopy, Suhai Yehuza (Gerrity)

Development of an apparatus for quantifying PAH and VOC production in electronic cigarettes, Jordan Yu (Walsh)

Biochemistry and Molecular Biology

Determination of BosR DNA binding sequence using CASTing method, Sofia-Mari Claesson (Glasfeld)

Reaction screening and optimization for use in a bismuth(III) asymmetric counterion directed catalysis system, Alyssa Harrison (LaLonde)

Spectroscopic analysis of the CusCFBA copper exporter in Escherichia coli, Ethan Ho (Chacón)

A tale of two proteins: towards cloning, expression, and purification of the bHLHZip domains of MondoA and Mlx, Erin McConnell (Glasfeld)

Towards an ideal green chemistry reaction: on the use of cationic organobismuth and tetraarylborate counteranion complexes in asymmetric alkylations, Johnny Mendoza (LaLonde)

Toward a complete understanding of copper efflux in Escherichia coli: a fluorescence-based investigation of metal transfer between CusF and CusB, Jonathan Perkins (Chacón)

Expression and purification of the putative Zn-dependent sulfatase AtsH from Mycobacterium tuberculosis, Natalie Stone (Glasfeld)

2015

Chemistry

Synthesis of Cobalt, Rhodium, and Iridium Acetyl(imino)pyridine Compounds for the Reductive Dehalogenaiton of Chlorinated Ethylenes, Mark Angeles (Kliegman)

Laser Induced Breakdown Spectroscopy: Brute Force Elemental Analysis, Arthur Chang (Gerrity)

DFT Analysis of a Platinacyclobutane Rearrangement, Megan Flood (Shusterman)

A Contribution to the Fight Against Malaria: Novel Synthesis and Characterization of 3-Alkylarylether-4(1H)-quinolones with Antimalarial Properties, Lisa Frueh (Glasfeld)

Towards Enantioselective Bismuth(III) Lewis Acid Catalysis via Utilization of a Chiral Counteranion Method for Asymmetric Induction, Drew Gingerich (LaLonde)

Size-Dependent Molecular-Level Characterization of Secondary Organic Aerosol from NO3 Initiated Δ-carene Oxidation using Nanospray Desorption Electrospray Ionization High-Resolution Mass Spectrometry, Hyun Kang (Fry)

Detecting Organic Nitrates Using Thermal Dissociation Cavity Ring-down Spectroscopy (TDCRDS), Natalie Keehan (Fry)

Predicting Depolarization Ratios and Relative Intensities for Resonance Raman spectroscopy Using the Irreducible Tensor Method, Kathleen Kruzich (Gerrity)

Natural Bond Orbital Analysis of the Congested Hydrogen-Hydrogen Interactions in exo-exo-Tentracyclododecane, Kata Martin (Shusterman)

Toward the Synthesis of a Novel Bismuth Catalyst Using Chiral BINOL-derived Phosphoric Acids to Effect Enantioselectivity Through Asymmetric Counterion-Directed Catalysis, Lukas Morick (LaLonde)

The Composition of Secondary Organic Aerosols at an Urban Site, Eve Mozur (Fry)

Binding Characteristics of FOX1 with Insulin Receptor RNA, Rachael Otto (Cass)

A Novel Approach to the Source Region Impact Factor Using Outputs from the Hybrid Single Particle Lagrangian Integrated Trajectory Model, Jonathan Tamsut (Walsh)

The Electrochemical Properties of Vitamin B12, a Reductive Dehalogenaiton Catalyst, Vania Wang (Kliegman)

Biochemistry and Molceular Biology

Green Toward a Synthesis of Bismuth Triacetazolamide: Activity against Helicobacter pylori, Stewart Green (LaLonde)

Determination of Actinomycin D’s role as an inhibitor in Myotonic Dystrophy Type 1, Shanee Harriott (Cass)

Towards an Understanding of Metal-Binding in Metal-Dependent Repressor 1 (MDR1) from Archaeoglobus fulgidus, Christina Johnson (Glasfeld)

Asp8 and the Metal-Binding Properties and Selective Activation of the Manganese Transport Regulator, Jacob Luton (Glasfeld)

Bi(III) Interaction with Helicobacter pylori Neutrophil Activating Protein: A foundation, Christopher Yan (Glasfeld)

Environmental Studies

Problematizing Trees: Ecosystem Analysis of Urban Trees’ Impact on Air Quality, G Luhman (Walsh)

2014

Chemistry

The air you breathe: A chemical characterization of the inorganic gas-aerosol system in the atmosphere above Portland, OR and Centerville, AL, Hannah Allen (Fry)

A Computational Analysis of the Kinetics of Trinaphthyl Methyl and Tri(2-Fluoro-1-Naphthyl) Methyl Cation Racemization, James Cahill (Shusterman)

NOx de Plume: A Spatial Analysis of Nitrogen Dioxide Plume Near the Brooklyn Railyard in Southeast Portland, Oregon, Christopher Cogell (Fry)

Towards the Synthesis of a Novel Chiral Ligand for Bismuth for Use in Asymmetric Catalysis, Emily Drew (LaLonde)

An Investigation into the Photocatalytic Activity of Molybdate and Tungstate Containing Mixed Metal Oxide Semiconductors, Lainey Fergusson (Geselbracht)

Toward a Novel Chiral Organobismuth Catalyst for Asymmetric Organic Transformations, Adriana Jemison (LaLonde)

Elucidating the Role of Acetic Acid in the Formation of Vanadium Pentoxide Gels from Triisopropoxy Vanadium(V) Oxide, Trevor Lohrey (Geselbracht)

Metal Binding Selectivity and the Role of Asp8 and Glu99 in Manganese Transport Regulator MntR, Will McKeen (Glasfeld)

Synthesis and Derivatization of a Red Shifted BODIPY scaffold for Super Resolution Microscopy, Vyom Shukla (Shusterman)

Structure and Electronic Properties of Low-Temperature Annealed Vanadium Pentoxide Sol-Gel Materials, Veronica Stewart (Geselbracht)

Towards a library of Catalytic Bismuth Cryptands: Self-Assembled Nanovessels and the Quest for Solubility in Aqueous Media, Kathleya Strode (LaLonde)

Biochemistry and Molceular Biology

MDR1: Characterization of an Archaeal Metal-Dependent Repressor found in Archaeoglobus Fulgidus, Adrian Dannis (Glasfeld)

A biochemical characterization of BosR, the Borrelia burgdorferi oxidative stresssensor, Talya Levitz (Glasfeld)

Synthesis and Biological Evaluations of N-acetyl-4’-sulfatoxy-3-iodothyronamine, Peter McTigue (Shusterman)

Towards the Total Synthesis of a Sesquiterpene Υ-Lactone Scaffolding, Ariana Remmel (LaLonde)

An Analysis of MBNL1 Zinc Finger Binding using Fluorescence Anisotropy, Erin Weisenhorn (Cass/Glasfeld)

The Search for an Ideal SERM: Towards the Design and Synthesis of a Novel Selective Estrogen Receptor Modulator, Rachel Yahn (LaLonde)

Environmental Studies

Observational Study of Brooklyn Rail Yard and its Effects on Air Quality in Portland, Alan Tuan (Fry)

2013

Chemistry

Effects of Thermal Annealing on the Structure and Electronic Properties of Sol-Gel Derived V2O5 Materials, Vaughn Cody (Geselbracht)

NO2 effects on nighttime secondary organic aerosol (SOA) formation, Danielle Draper (Fry)

Three Stereocenters, One Product: A Computational Study of a Stereoselective Amine-Catalyzed Diels-Alder Reaction, Emma Farley (Shusterman)

Electrical Properties of V2O5 thin Films Synthesized from the Sol-Gel Method, Malkolm Graffe (Geselbracht)

A Journey into the Unknown Exploring Manganese Specificity in ManS, Evan Green (Glasfeld)

Investigating the Potential Photocatalytic Activity of Molybdates and Tungstates, Nicole Horbinski (Geselbracht)

Exploring the Activation Mechanism of ScaR Through Mutations to its Metal Binding Sites, Erin Jacot (Glasfeld)

A Series of Unfortunate Compounds Improving the Solubility of Host-Targeted Antivirals for In Vivo Testing, Ilsa Kirby (Nilsen)

Adventures in Field Work: A Quantitative Analysis of Ambient Organic Aerosol Composition by FTIR with Meterological and Gas-phase Oxidant Characterization in the Columbia River Gorge, Laura Krause (Fry)

An Investigation into the Metal-Binding Properties of the Manganese Transporter MntA, Rhiana Meade (Glasfeld)

Towards the Eradication of Malaria: Novel Introduction of Acid Sensitive Functionality in Endochin-Like-Quinolones, Galen Miley (Nilsen)

A Novel Synthetic Route to Porous V2O5, Ellen Murphy (Geselbracht)

Calculating Depolarization Ratios through the Irreducible Tensor Method for Dipole-Forbidden Resonance Raman Spectroscopy, Neha Rao (Gerrity)

Synthetic Models for Second-Generation Monoterpene Chemistry in NO3-Influenced Aerosol Formation, Kathryn Sackinger (Fry)

On the Development and Synthesis of Thienopyridine Dengue Antivirals: A Novel Approach to a Neglected Problem, Kayla Sheridan (Nilsen)

Biochemistry and Molceular Biology

The N-Terminal Helix and DNA Binding by the Manganese Transport Regulator MntR, Rachel Baden (Glasfeld)

Effect of Structural Variation of Quinolone-3-diarylethers on Cytochrome bc1 Selectivity, Jeffrey Hamada (Nilsen)

Characterization of RNA-binding by MBNL zinc fingers ½ using fluorescene anisotropy, Anna Henkin (Glasfeld)

A Crystallographic Study of SloR, Dillon Nye (Glasfeld)

Environmental Studies

Monitoring the Ozonolysis of α-Pinene Using GC/FID, James Bianconi (Fry)

2012

Chemistry

Progress Towards the Development of an Organic Amidation Catalyst, Christopher Cahill (Boisvert)

Effects of Copper Exposure on Intracellular Calcium Distribution in a Wilson and Menkes Disease Human Fibroblast Cell Model, Megan Duffy (Glasfeld)

Ligand Influence on Catalysis of Amidation by Tertiary Arsine Oxides, Alina Kassenbrock (Boisvert)

N-Sulfonycyclobutylimines as Metal-Free Alkene Metathesis Catalyst Precursors, Joshua Katz (Boisvert)

Conformational Dynamics of MntR: Evidence from the Y95W-W107Y Mutant, Dana Loutey (Glasfeld)

Probing the role of annealing atmosphere in the lithium ion insertion behavior of V2O5, Sibongile Malunga (Geselbracht)

Organosulfate Standards for Ambient Aerosol Analysis: Synthesis and Quantification, Andrew Maser (Galloway)

Protein Crystallography of the Drosophila Muscleblind Alternative Splicing Factor, Jayasri Narasimhan (Cass)

Screening and Phase Identification of Metal Oxide Semiconductors for Water Photoelectrolysis, Elizabeth Ogden (Geselbracht)

Toward NMR Spectroscopy of NF1, a zinc finger, Paul Whittredge (Glasfeld)

Probing the Role of Annealing Temperatures in the Li+ Ion Insertion Behavior of V2O5, Li Zha (Geselbracht)

Biochemistry and Molceular Biology

A New Approach to the Synthesis and Pharmacokinetics of the Novel Thyroid Hormone Receptor Antagonist NH-3, Michael Gonzales (Glasfeld)

Copper Redistribution in Early Stages of Wilson’s Disease: Understanding Copper Hot-Spots in Atp7b-/- Mouse Livers, Emily Robinson (Glasfeld)

Identifying the metal ion specificity of the Staphylococcal iron regulator repressor (SirR), Rukayat Taiwo (Glasfeld)