Chemistry Department

Senior Thesis Titles

Recent senior theses are listed here by title, student name, faculty advisor. A complete listing of thesis titles is available via the on-line catalog of the Reed College library.

2018

Chemistry

Harnessing light : synthesis of a polymeric DASA, Maggie Asher (Helmy

Elucidating the time-resolved photoluminescence properties of carbon dots, Thanh Chu (Chatterjee)

Hot rocks in space : verifying onset processes in the thermal metamorphism of unequilibrated ordinary chondrites, Orion Cohen (Swartz)

Molecular building blocks : peptide self-assembly and pigmentation, Dashiel Grusky (Chatterjee)

The influence of chemical composition on viscoelastic and acoustic properties of microbubble contrast agents, Matthew Muller (Gerrity)

A supramolecular approach to bismuth catalysis, Johnathan Sheiman (LaLonde)

Evaluating a central nervous system permeant prodrug of sobetirome as a novel treatment for x-linked adrenoleukodystrophy, Mitra Shokat (Glasfeld)

Characterization of weathered inks on glass and paper as an analogue for materials found in historic texts, Kathryn Stellmach (Swartz)

Synthesis of a heterobimetallic iridium-ruthenium organometallic complex towards the investigation of a large kinetic isotope effect, Joshua Tsang (Bowring)

Optimization of calibration-free laser-induced breakdown spectroscopy for the rapid classification of meteorites under ambient conditions, Oliver Wass (Swartz)

On the photochromism of 4,4'-divinylazobenzene and its crosslinked polymers, Anton Zaystev (Helmy)

Chemistry-Physics:

Characterizing the elastic responses of double stranded DNA through direct observation atomic force microscopy, Davis Kusnick (Essick and Glasfeld)

Correcting for coincidence : applying a semi-empirical correction scheme for coincidence summing in [gamma]-ray spectroscopy, Amanda Swanson (Smith and Gerrity)

Biochemistry and Molecular Biology

An investigation of the effect of methionine and histidine ligands in facilitating the Cu(I) transfer reaction between CusB and CusF in Escherichia coli, Sarah Brodesser (Chacón)

Investigations into BosR, a Borreli burgdorferi DNA binding protein, Mia Galbraith-Liss (Glasfeld)

Production of the Helicobacter pylori neutrophil activating protein A (NapA) in Escherichia coli, Thomas Hoang (Glasfeld)

Have you heard about terD : the characterization and investigation of proteins expressed from the ter operon, Akanksha Majumdar (Chacón)

Accumulation of manganese in the pituitary gland and its effects on annexin a2, Georgia Wong (Glasfeld)

Environmental Studies: Chemistry

Source apportionment of trace elements and black carbon in particulate matter in Southeast Portland, OR, Anna Miller (Fry)

What the heck : collection and quantification of anthropogenically emitted palladium in Portland, OR, Hunter Wise (Bowring)

 

2017

Chemistry

An Airshed and Source Region Impact Factor Tool Utilizing Output from the NOAA HYSPLIT Model, Amanda Asato (Walsh)

Synthesis of An Intramolecular DASA Photoswitch, Dakoda Bradley (Helmy)

Extraction and Measurement of Vitamin K in Blood Plasma using HPLC-MS/MS, Vivia Chi (Walsh)

Direct Conversion of Visible Light to Mechanical Energy: Towards Dimerized Donor-Acceptor Stenhouse Adducts as Photochromic Molecular Actuators, Audrey Dannar (Walsh)

The Synthesis and Characterization of Novel Decoquinate Analogs with Significant Antimalarial Activity, Rose Gonoud (Shusterman)

A Dusty Road: Palladium Catalysis via the Mizoroki-Heck Reaction, Oleksandr Lushchyk (Bowring)

Synthesis of an Iridium Hydride Complex: Towards a Model System for Hydrogen Tunneling, Zachary Mathe (Bowring)

An ab initioValence Bond Study of Charge-Shift Bonding in ortho-Benzyne, Brent Michel (Shusterman)

Methods for Analysis of Extended X-ray Absorption Fine Structure in Biochemical Systems: Demeter and EXCURV, Cat Neshyba (Chacón)

Cd and As: Impact of Long-term Atmospheric Deposition on Reed Canyon Soil Quality, Modi Raduma (Walsh)

Toward a NIR Photoswitch, Melinda Serrato (Helmy

Biochemistry and Molecular Biology

Toward the Development of Substrate-based Inhibitors of Mycobacterium tuberculosisLipase, LipY, Clara Herrera (Glasfeld)

Synthesis of Gemcitabine Derivatives for Use in Understanding Pancreatic Cancer Heterogeneity and Drug Resistance, Jamie Kim (Chacón)

Investigating the DNA Binding of the Metalloregulator SloR, Foster Seybert (Glasfeld)

The Restricted Section: Towards a Structure of the Restriction Enzyme Xhol, August Staubus (Glasfeld)

Towards an Understanding of BosR via CASTing Method and Structural Analysis, Weekie Yao (Glasfeld)

Environmental Studies: Chemistry

Source Apportionment of Airborne Heavy Metals at the Brooklyn Rail Yard in Portland, OR, Annelise Hill  (Fry)

LC-MS/MS Analysis of Imidacloprid in Oregon Honey, Lauren Kupper (Walsh)

 Urban Metals: Just a Hop, Skip and a Beer Away, Claire Young (Glasfeld)

2016

Chemistry

Pulsed Nd: YAG laser Raman spectroscopy and normal coordinate analysis of trivalent bismuth complexes, Joohee Bang (Gerrity)

Elucidating the water reducing mechanism of bis-2-mercaptopyridine-N-oxide nickel(II) as a model for the design of next generation water reducing catalysts, Carlo Berti (Kliegman)

Spinosad analysis of apples in the Pacific Northwest, Nich Hanson (Cass)

Couches on fire!: polybrominated diphenyl ethers and your dorm room, Jesyca Hernstadt (Kliegman)

Coal trains and the world: modeling the dispersion of fine particulate matter in the Columbia River Gorge, Katherine Jentoft-Herr (Walsh)

Tropospheric particle formation in forests: global modeling of secondary organic aerosol production from reaction of NO3 radical with speciated monoterpenes, Makoto Kelp (Fry)

Separation and quantification of radioactive 14C from irradiated graphite, Ilana Novakoski (Walsh)

Probing the activity of bismuth phosphates for asymmetric catalysis, Nick Till (LaLonde)

Preparing and characterizing bis(imino)pyridine complexes of nickel, iron and cobalt for electrocatalytic hydrogen evolution, Sam Underwood (Kliegman)

Proteins, DNA, electrons, and a little bit of uranium : protein·DNA complexes and cryo-electron microscopy, Jazz Weisman (Glasfeld)

Quantitative analysis of liquid matrices using laser-induced breakdown spectroscopy, Suhai Yehuza (Gerrity)

Development of an apparatus for quantifying PAH and VOC production in electronic cigarettes, Jordan Yu (Walsh)

Biochemistry and Molecular Biology

Determination of BosR DNA binding sequence using CASTing method, Sofia-Mari Claesson (Glasfeld)

Reaction screening and optimization for use in a bismuth(III) asymmetric counterion directed catalysis system, Alyssa Harrison (LaLonde)

Spectroscopic analysis of the CusCFBA copper exporter in Escherichia coli, Ethan Ho (Chacón)

A tale of two proteins: towards cloning, expression, and purification of the bHLHZip domains of MondoA and Mlx, Erin McConnell (Glasfeld)

Towards an ideal green chemistry reaction: on the use of cationic organobismuth and tetraarylborate counteranion complexes in asymmetric alkylations, Johnny Mendoza (LaLonde)

Toward a complete understanding of copper efflux in Escherichia coli: a fluorescence-based investigation of metal transfer between CusF and CusB, Jonathan Perkins (Chacón)

Expression and purification of the putative Zn-dependent sulfatase AtsH from Mycobacterium tuberculosis, Natalie Stone (Glasfeld)

2015

Chemistry

Synthesis of Cobalt, Rhodium, and Iridium Acetyl(imino)pyridine Compounds for the Reductive Dehalogenaiton of Chlorinated Ethylenes, Mark Angeles (Kliegman)

Laser Induced Breakdown Spectroscopy: Brute Force Elemental Analysis, Arthur Chang (Gerrity)

DFT Analysis of a Platinacyclobutane Rearrangement, Megan Flood (Shusterman)

A Contribution to the Fight Against Malaria: Novel Synthesis and Characterization of 3-Alkylarylether-4(1H)-quinolones with Antimalarial Properties, Lisa Frueh (Glasfeld)

Towards Enantioselective Bismuth(III) Lewis Acid Catalysis via Utilization of a Chiral Counteranion Method for Asymmetric Induction, Drew Gingerich (LaLonde)

Size-Dependent Molecular-Level Characterization of Secondary Organic Aerosol from NO3 Initiated Δ-carene Oxidation using Nanospray Desorption Electrospray Ionization High-Resolution Mass Spectrometry, Hyun Kang (Fry)

Detecting Organic Nitrates Using Thermal Dissociation Cavity Ring-down Spectroscopy (TDCRDS), Natalie Keehan (Fry)

Predicting Depolarization Ratios and Relative Intensities for Resonance Raman spectroscopy Using the Irreducible Tensor Method, Kathleen Kruzich (Gerrity)

Natural Bond Orbital Analysis of the Congested Hydrogen-Hydrogen Interactions in exo-exo-Tentracyclododecane, Kata Martin (Shusterman)

Toward the Synthesis of a Novel Bismuth Catalyst Using Chiral BINOL-derived Phosphoric Acids to Effect Enantioselectivity Through Asymmetric Counterion-Directed Catalysis, Lukas Morick (LaLonde)

The Composition of Secondary Organic Aerosols at an Urban Site, Eve Mozur (Fry)

Binding Characteristics of FOX1 with Insulin Receptor RNA, Rachael Otto (Cass)

A Novel Approach to the Source Region Impact Factor Using Outputs from the Hybrid Single Particle Lagrangian Integrated Trajectory Model, Jonathan Tamsut (Walsh)

The Electrochemical Properties of Vitamin B12, a Reductive Dehalogenaiton Catalyst, Vania Wang (Kliegman)

Biochemistry and Molceular Biology

Green Toward a Synthesis of Bismuth Triacetazolamide: Activity against Helicobacter pylori, Stewart Green (LaLonde)

Determination of Actinomycin D’s role as an inhibitor in Myotonic Dystrophy Type 1, Shanee Harriott (Cass)

Towards an Understanding of Metal-Binding in Metal-Dependent Repressor 1 (MDR1) from Archaeoglobus fulgidus, Christina Johnson (Glasfeld)

Asp8 and the Metal-Binding Properties and Selective Activation of the Manganese Transport Regulator, Jacob Luton (Glasfeld)

Bi(III) Interaction with Helicobacter pylori Neutrophil Activating Protein: A foundation, Christopher Yan (Glasfeld)

Environmental Studies

Problematizing Trees: Ecosystem Analysis of Urban Trees’ Impact on Air Quality, G Luhman (Walsh)

2014

Chemistry

The air you breathe: A chemical characterization of the inorganic gas-aerosol system in the atmosphere above Portland, OR and Centerville, AL, Hannah Allen (Fry)

A Computational Analysis of the Kinetics of Trinaphthyl Methyl and Tri(2-Fluoro-1-Naphthyl) Methyl Cation Racemization, James Cahill (Shusterman)

NOx de Plume: A Spatial Analysis of Nitrogen Dioxide Plume Near the Brooklyn Railyard in Southeast Portland, Oregon, Christopher Cogell (Fry)

Towards the Synthesis of a Novel Chiral Ligand for Bismuth for Use in Asymmetric Catalysis, Emily Drew (LaLonde)

An Investigation into the Photocatalytic Activity of Molybdate and Tungstate Containing Mixed Metal Oxide Semiconductors, Lainey Fergusson (Geselbracht)

Toward a Novel Chiral Organobismuth Catalyst for Asymmetric Organic Transformations, Adriana Jemison (LaLonde)

Elucidating the Role of Acetic Acid in the Formation of Vanadium Pentoxide Gels from Triisopropoxy Vanadium(V) Oxide, Trevor Lohrey (Geselbracht)

Metal Binding Selectivity and the Role of Asp8 and Glu99 in Manganese Transport Regulator MntR, Will McKeen (Glasfeld)

Synthesis and Derivatization of a Red Shifted BODIPY scaffold for Super Resolution Microscopy, Vyom Shukla (Shusterman)

Structure and Electronic Properties of Low-Temperature Annealed Vanadium Pentoxide Sol-Gel Materials, Veronica Stewart (Geselbracht)

Towards a library of Catalytic Bismuth Cryptands: Self-Assembled Nanovessels and the Quest for Solubility in Aqueous Media, Kathleya Strode (LaLonde)

Biochemistry and Molceular Biology

MDR1: Characterization of an Archaeal Metal-Dependent Repressor found in Archaeoglobus Fulgidus, Adrian Dannis (Glasfeld)

A biochemical characterization of BosR, the Borrelia burgdorferi oxidative stresssensor, Talya Levitz (Glasfeld)

Synthesis and Biological Evaluations of N-acetyl-4’-sulfatoxy-3-iodothyronamine, Peter McTigue (Shusterman)

Towards the Total Synthesis of a Sesquiterpene Υ-Lactone Scaffolding, Ariana Remmel (LaLonde)

An Analysis of MBNL1 Zinc Finger Binding using Fluorescence Anisotropy, Erin Weisenhorn (Cass/Glasfeld)

The Search for an Ideal SERM: Towards the Design and Synthesis of a Novel Selective Estrogen Receptor Modulator, Rachel Yahn (LaLonde)

Environmental Studies

Observational Study of Brooklyn Rail Yard and its Effects on Air Quality in Portland, Alan Tuan (Fry)