Comparative Functional Genomics
Biology 431 Spring 2008
Februray 7th 2008
Metagenomics and Next-Generation Sequencing Techniques
He joined the core in 1995 after running a similar facility at University
of Wisconsin, Madison for five years.
If you are not familiar with "old style" DNA sequencing, known
as Sanger Sequencing, I suggest a quick look at a web page posted by
Davidson College. http://www.bio.davidson.edu/Courses/Bio111/seq.html
For a quick "history" of these "Next-Gen" techniques and a quick overview
upon which Tom will elaborate please read the following short pieces.
Following the presentation:
Cox-Foster et al., (2007) A Metagonimc Survey of Microbes in Honey Bee Colony Collapse Disorder. Science 318:283-287.
We have to quickly take care of business:
Following that presentation and discussion, if there is time, we can watch part of a video about the Sorcer II Global Ocean Sequencing Project. Although this metagenomics project has used Sanger Sequencing techniques so far, I feel that Craig Venter, and this team, are a phenomenon worth knowing about.
I will spare you reading the scientific publications from the Sorcerer II project, though I encourage you to look through them.
et al., (2007) The Sorcerer II Global Ocean Sampling Expedition:
Expanding the Universte of Protein Families. PLoS Biology 5:e16.