Students

Beyond Reed

Thesis students from my lab have gone on to the following:

Graduate Programs
Emory University, University of California at Davis, University of California, Berkeley, University of Michigan, Johns Hopkins University, University of California, San Francisco, Dartmouth College, Rockefeller University, University of Pennsylvania, Harvard University, and Stanford University.

Medical Schools
University of Maryland School of MedicineTulane University School of Public HealthGeorge Washington University School of MedicineOregon Health & Science UniversityUniversity of Arizona College of Medicine, The University of Oklahoma, and Albert Einstein College of Medicine.

Biotechnology
MedImmune, Inc., Silver Lake Research Corporation and Biovest International.

Law School
Santa Clara University, Duke University School of Law.

Public Health
Tulane University School of Public Health and Tropical Medicine and University of California, Berkeley, School of Public Health.

Veterinary Schools
Tufts University and Massey University

Awards

Jossef Osborn ('15) 
The Reed President's Winter Fellowship to visit the South African Tuberculosis Vaccine Initiative, 2014-2015

Rosie Lawrence-Pine ('11)
ASM Undergraduate Research Fellowship, 2010-2011

Jeannette Tenthorey ('09)
NSF Graduate Fellowship, 2012

Anna Carmona ('06)
Best Undergraduate Research Poster Presentation at the Northwest Branch
Meeting of the American Society for Microbiology, Seattle, Washington,
March 10-12, 2006.

Alex Barron ('05)
Student Travel Award - ASM General Meeting, Atlanta, Georgia, June 2005

Derek Galligan ('05)
ASM Undergraduate Research Fellowship, 2004-2005

Kristin Harper ('02)
Student Travel Award - ASM General Meeting, Salt Lake City, Utah, May 2002
NSF Graduate Fellowship ('03) and Howard Hughes Medical Institute Pre-Doctoral Fellowship ('03)

Leslie Hoover ('01)
NIH Post-Baccalaureate Research Fellowship, Bethesda, Maryland, 2001-2003

Presentations

Hirata, K, Zhang , Y, Nan, X and J Mellies. Ler’s In Vivo Oligomerization in Pathogenic Escherichia coli. Presented General Meeting of the American Society for Microbiology, New Orleans, June 1-5, 2017.

Cepko, L, Garling, E, and J Mellies. The Age of Phage in Portlandia: Allopatric Isolation and Genomic Characterization of Siphoviridae Phage that kill E.coli pathotypes. Presented at the Molecular Genetics of Bacteria and Phages Meeting, University of Wisconsin, Madison, August 8-12, 2016.

Mellies, J, Platenkamp, A, Ben-Avi, L, and J Osborn. PerC Manipulates Metabolism and Surface Antigens in Enteropathogenic Escherichia coli. Presented at the Molecular Genetics of Bacteria and Phages Meeting, University of Wisconsin, Madison, August 8-12, 2016.

Weinstein, J, Yan, J, and JL Mellies. I48R substitution in the Ler linker of enteropathogenic Escherichia coli diminishes in vivo activity. Presented General Meeting of the American Society for Microbiology, New Orleans, May 30 – June 2, 2015.

Xue, Y, Osborn, J and JL Mellies. Molecular mechanism of zinc disruption of Enteropathogenic Escherichia coli pathogenesis. Presented at The Microbial Toxins & Pathogenicity Gordon Research Conference, Waterville Valley, NH, July 20-25, 2014.

Mellies, JL, Lawrence-Pine, R, Gilbert, M, and R Strominger. The plasmid-encoded regulator PerC stimulates central metabolism in enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Denver, May 18-21, 2013.

Lawrence-Pine, R and J Mellies. Over-expression of YqeF, a putative acetyl-CoA acetyltransferase, causes auto-aggregation in enteropathogenic Escherichia coli. Presented at the Molecular Genetics of Bacteria and Phage Meeting, Madison, WI, August 2-7, 2011.

Turvey, M, Thomas, K, Crane, J, Boedecker, E, and J Mellies. The Regulatory Network Controlling Zinc Inhibition of the LEE of Enteropathogenic Escherichia coli. Presented at the General Meeting of the American Society for Microbiology, New Orleans, Louisiana, May 21-24, 2011.

Mellies, JL, Boniface, C, Lorenzen, E and G Benison. Structural Analysis of the N-Terminal and C-Terminal Domains of Ler in Enteropathogenic Escherichia coli. Presented at the General Meeting of the American Society for Microbiology, San Diego, California, May 23-27, 2010.

Mellies, J, Tenthorey, J, Mavor, D, Boniface, C, and J Connell. Molecular features of Ler that distinguish the protein from H-NS. Presented at the Molecular Genetics of Bacteria and Phage Meeting, Madison, WI, August 4-9, 2009.

Mellies, JL, Larabee, F, Fowlkes, J, Horback, K, and M Zarr. The Ler Linker Domain is Necessary for Anti-Silencing Activity in Enteropathogenic Escherichia coli. Presented at the General Meeting of the American Society for Microbiology, Boston, June 1-5, 2008.

Mellies, JL, Larabee, F, Haack, K, and D Mavor. The Ler Linker Domain Is Essential for Anti-Silencing Activity in Enteropathogenic Escherichia coli. Presented at the Molecular Genetics of Bacteria and Phage Meeting,
Madison, WI, August 7-12, 2007.

Kreston, RJ, Barron, MS and JL Mellies. Using the Nematode Caenorhabditis elegans to Model Enterotoxigenic Escherichia coli Infection. Presented at the General Meeting of the American Society for Microbiology, Toronto, Canada, May 20-25, 2007.

Mellies, JL, Haack, K and DC Galligan. SOS Regulation of the Type III Secretion System of Enteropathogenic Escherichia coli. Presented at the Gordon Research Conference on Microbial Stress Response, Mt. Holyoke College, South Hadley, Massachusetts, July 9-13, 2006.

Carmona, A.M., Glasfeld, A., and JL Mellies. Molecular Mechanism of LEE5 Transcription in Enteropathogenic Escherichia coli: in vitro Analysis of H-NS and Ler Binding. Presented at the Northwest Branch Meeting of the American Society for Microbiology, Seattle, Washington, March 10-12, 2006.

Barron, A, Haack, K, and JL Mellies. Caenorhabditis elegans as a Model for Enteropathogenic Escherichia coli Infection. Presented at the General Meeting of the American Society for Microbiology, Atlanta, Georgia, June 5–9, 2005.

Galligan, D, Haack, K, and JL Mellies. Regulation of EPEC Virulence Genes by DNA Damage Signaling. Presented at the General Meeting of the American Society for Microbiology, Atlanta, Georgia, June 5–9, 2005.

Barron, A, Galligan, D , and JL Mellies. Caenorhabditis elegans as a Model Host for Enteropathogenic Escherichia coli (EPEC) Pathogenesis. Presented at the Northwest Branch Meeting of the American Society for Microbiology, Vancouver, British Columbia, Canada, August 8-10, 2003.

Mellies, JL, Ceesay, A, Fowlkes, J, and Haack, K. Ler and H-NS Mediated Regulation of the LEE5 (tir) Operon in Enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Washington, D.C., May 18-22, 2003.

Harper, KN and L Hoover, K Haack, I Okeke and JL Mellies. Sucrose Utilization in Enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Salt Lake City, Utah, May 19-23, 2002

Mellies, JL, CL Robinson, K Haack, K Miller, and K Harper. Mechanism of Ler-Mediated Activation of tir in Enteropathogenic E. coli. Presented at the General Meeting of the American Society for Microbiology, Salt Lake City, Utah, May 19-23, 2002.

Selected Senior Theses

Turning a New Phage
By Eliotte Garling, May 2018

How I (fluorescently) quenched my thirst for Ler-ning
By Katie McPherson, May 2018

Plastic Pollution and Bacterial Solutions
By Morgan Vague, December 2018

Effects of PerC regulation and membrane vesicles of enteropathogenic Escherichia coli on a pro-inflammatory response
By Vikram Chan-Herur, May 2017

Distribution of the Transcriptional Regulator Ler in E. coli Using PALM
By Kristin Hirata, May 2017

A tale of two phages: Investigation of the therapeutic potential of SiphoRed1 and SiphoRed2
By Madeline Dinsdale, May 2017

Cohabitation to Restore the Rat Microbiome after Antibiotic-Induced Dysbiosis
By Yasemin Lopez, May 2017

The Age of Phage
By Leah Cepko, May 2016

Regulation of anaerobic respiration by PerC in enteropathogenic Escherichia coli
By Amy Platenkamp, May 2016

The Role of Hfq in the Reduction of Virulence in EPEC by Zinc
By Maggie Cheney, May 2015

Whole-Transcriptome Analysis of the PerC Regulon Identifies Novel Niche-Adaptive Mechanisms in enteropathogenic Escherichia coli
By Jossef Osborn, May 2015

Altering Ler Linker Hydrophobicity Diminishes Regulatory Activity
By Jules Weinstein, May 2015

PerC Enhances Oxidative Stress Response in Enteropathogenic Escherichia coli
By Karen Dewey, May 2014

Using Bacteriophages to Clear Bacterial Biofilms
By Jennifer Farrell, May 2014

Understanding the Mechanism of ler Regulation by PerC
By Gus Kilgore, May 2014

Hydrophobicity of the Ler Linker is Necessary for Transcriptional Activation
By Abe Leiser, May 2014

The Sigma E-Dependent Pathway of Enteropathogenic Escherichia coli Mediates Inhibition of LEE Virulence by Zinc
By Yuan Xue (Soso), May 2014

Zinc as a Therapeutic Agent in Enteric Infections
By Anand Panchal, May 2013