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Reed receives National Science Foundation grant for biology This multi-year grant will provide a long-range, coherent framework and the resources for students
to learn to build on the work of others, either in summer or thesis projects. The links between telomere
function and cellular senescene/ immortalization of cancer cells were byproducts of investigations
into DNA replication at chromosome ends. |
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The National Science Foundation awarded a grant of $115,900 to Reed College for
the project “RUI:
Telomere Function and Dysfunction In Vivo,” under the direction of biology professor Janis Shampay.
Reed students will work with Shampay to identify and clone telomere (chromosome ends) binding protein
genes from Xenopus laevis and the true diploid Xenopus tropicalis, using EST database mining and molecular
techniques to amplify the genes from messenger RNA. Cloned gene products will then be tested for telomere
binding capability. Lastly, the function of the genes will be disrupted, using the new technique of short
interfering RNA.