Syllabus

WEEK DATE LECTURE READING
1 8-28
8-30
Introduction to Immunology
Cells of the immune system and lymphoid organs
Ch. 1
Ch. 2
2 9-4
9-6
Innate immunity I
Innate immunity II
Ch. 3
3 9-11
9-13
Complement system / HW1 DUE
Adaptive Immunity
Ch. 7
Ch. 8
4 9-18
9-20
MHC restriction and thymic selection
Dendritic cells
Ch. 8
Heesters et al., 2014
5 9-25
9-27
Antigen processing and presentation
Immunoglobulin rearrangement / HW2 DUE
Ch. 6 and Kloetzel 2001
Ch. 5
6 10-2
10-4
T cell differentiation and response
B cell activation and humoral immunity
Ch. 10
Ch. 11
7 10-9
10-11
ESSAY 1
Tolerance and autoimmunity
Ch. 16 and Onishi et al. 2008
FALL BREAK    
8 10-23
10-25
Applications
Lab Lecture
Ch. 22
Boyman and Sprent 2012
9 10-30
11-1
LAB I: IL-2 in splenocytes
Tumor immunology (freeze IL-2 samples)

Ch. 21
10 11-6
11-8
Transplantation
LAB II: ELISA to detect IL-2
Ch. 17
11 11-13
11-15
Mucosal immunity / HW3 DUE
Immunity to viruses
Turner et al. 2009
Ch. 18
12 11-20
11-22
HIV targets CD4 T cells 
THANKSGIVING
Ch. 20 and Doitsh et al. 2014
13 11-27
11-29
Vaccinology / LAB REPORTS DUE
Tim Nice, Ph.D.
Ch. 19
Nice et al. 2018
12-4 Primary research article – class choice Warfel et al. 2016
  12-13 FINAL ESSAY EXAM DUE