Works and Days

Wehrli Lab Notes, Daniel Lybrand '13

I am currently working at OHSU in the lab of Marcel Wehrli, Ph.D. The lab studies development in Drosophila (fruit flies) and focuses on the Wnt signaling pathway, one that features prominently in developmental biology research. My first week at OHSU has introduced me to a completely new area of biology. Most of my prior research experience has been in plant physiology. I have never worked with Drosophila before and know almost nothing about their development, so I am guaranteed to learn something new every day.

As a novice in the field, I learn from both Marcel and his research assistant, Misha (also a Reedie). I don’t yet have a project of my own, so I usually assist Misha with her experiments. Some of what I learn is completely new – techniques that I have never seen before.

In the past week, I have learned how to distinguish between male and female flies, how to tell a virgin from a fly that has never mated, how to dissect a fly larva, and how to identify the imaginal discs within the larva that eventually develop into various appendages. Other things are familiar but must be re-learned, as different labs carry out basic protocols in different ways. Antibody staining fruit fly larvae is very different from staining plant tissues!

I have no prior research experience in this area, but that isn’t important. What is important is demonstrating the ability to learn a new skill-set rapidly and the drive to study the basics of a new field outside of a classroom setting. I look forward to having my own Drosophila project to look after soon.

Tags: internship advantage

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